Strength
DEFRATAJ 125 mg - Deferasirox
Dispersible Tablet · Oral (after dispersion)
DEFRATAJ 125 mg
Deferasirox Dispersible Tablet
| Product Name | Deferasirox Dispersible Tablet 125 mg |
|---|---|
| Brand Name | DEFRATAJ |
| Strength | 125 mg |
| Dosage Form | Dispersible Tablet |
| Route of Administration | Oral (after dispersion) |
| Packing | 10 x 10 PVC/PVDC-Aluminium blisters; HDPE bottles available; custom pack sizes for tenders |
| Shelf Life | 24-36 months (market-specific) |
| Therapeutic Use | Iron chelator (ATC: V03AC03) for chronic transfusional iron overload |
| Indication | Treatment of chronic iron overload due to frequent blood transfusions in pediatric and adult patients with beta-thalassemia major, sickle-cell disease and other transfusion-dependent anemias. Useful for intermediate pediatric titration steps. |
| Storage | Store below 30 degrees C. Protect from moisture. |
| Composition | Each dispersible tablet contains: Deferasirox 125 mg. Excipients: lactose monohydrate, microcrystalline cellulose, crospovidone, povidone K30, sodium lauryl sulfate, colloidal silicon dioxide, magnesium stearate. |
| Tablet Description | Off-white to pale yellow, round, flat, uncoated tablet with break-line; disperses rapidly in water or juice. |
Full Excipient Breakdown
| Excipient | Function |
|---|---|
| Lactose monohydrate | Diluent |
| Microcrystalline cellulose | Diluent / binder |
| Crospovidone | Disintegrant |
| Povidone K30 | Binder |
| Sodium lauryl sulfate | Wetting agent |
| Colloidal silicon dioxide | Glidant |
| Magnesium stearate | Lubricant |
Dosage Instructions
Disperse in 100-200 ml of water, orange juice or apple juice; drink immediately. Once daily, on empty stomach, at the same time daily.
Caution & Warning
Schedule H drug. Sold by prescription only. Monitor renal/hepatic function. Discontinue on signs of SJS/TEN/DRESS or organ failure. Not for use when CrCl < 60 mL/min.
Overdose
No specific antidote. Doses up to 80 mg/kg tolerated. Supportive management. Dialysis unlikely effective.
Disposal
Dispose per local pharmaceutical-waste regulations. Not via wastewater or household refuse.
The 125 mg strength complements the 100 mg unit for fine pediatric dose titration and provides flexibility when patient weight does not align cleanly with 100 mg increments.
Schedule H: To be sold by retail on the prescription of a Registered Medical Practitioner only.
Not all pack sizes may be marketed.